ALL statements made here are OPINIONS only!
Peptides are listed in Alphabetical Order!
5-Amino-1MQ
Build muscle AND burn fat. Boosts metabolism. Increase exercise performance. Takes 2-4 weeks before noticing anything. Body adjusts after 6 weeks, reducing effect. Therefore, recommend stopping after about a month. Can stack with BPC-157, CJC-1295, Ipamorelin.
Dosage: 1mg per day
10mg vial with 2cc BAC = 20 units per mg.
AOD-9604
Weight loss. Bone and cartilage regeneration. Boosts metabolism.
This peptide possibly aids in the prevention and possible treatment of osteoporosis, through direct action on osteoblasts, the cells which build new bone. Also, many clinics combine it with hyaluronic acid injections, because studies show AOD-9604 aids in cartilage regeneration. Among other uses, I recommend this peptide after any PRP, Stem Cells, or Exosomes treatments.
AOD-9604 is the synthesized fragment of human growth hormone (specifically it’s the last 15 molecules on the chain). Half life 8-10 hours. AOD-9604 doesn’t down-regulate your own endogenous growth hormone production like HGH injections will.
AOD-9604 works best when you are in a calorie deficit. If you have stalled on a GLP-1 (tirzepatide, retatrutide), then AOD-9604 is very effective at breaking the stall. It also helps reduce visceral fat. It combats insulins blockage of your fat cells, making it easier for your body to metabolize fat.
There’s a study in Growth Hormone and IGF Research that shows AOD-9604 significantly up-regulates the production of chondrocytes, which are the only cells in your body that can produce cartilage. It has been shown to stimulate the synthesis of cartilage type 2 and aggrecan, which means it might help you avoid a knee replacement!
Here is a research article showing the efficacy of AOD-9604 (combined with chemo) in cancer treatment: https://pmc.ncbi.nlm.nih.gov/articles/PMC9249349/
Use BPC-157, AOD-9604, and MOTS-c togetherfor bone mineral density improvement.
Dosage: 2-3 times per day. 250-600mcg per day. Before eating, and before exercise. Fasted morning is best.
6mg vial, with 2cc BAC = 450mcg per 15 units.
ARA-290
Across all neuropathy trials, ARA-290 consistently had these benefits:
1. Symptom relief – less burning, tingling, and pain.
2. Objective repair – actual regrowth of damaged small nerve fibers seen under the microscope
In patients with diabetes, ARA-290 also improved metabolic markers such as glucose and triglycerides, likely by reducing inflammation at the cellular level.
Based on the data, the people most likely to benefit from ARA-290 are:
- Patients with sarcoidosis and small-fiber neuropathy, especially those with confirmed nerve fiber loss and significant pain.
- People with type 2 diabetes and painful neuropathy, particularly in early stages when there is still nerve tissue left to repair.
- Anyone with documented small-fiber damage on skin biopsy or corneal imaging and an inflammatory component to their condition.
Dosage: All human trials used subcutaneous injections. The effective dose was 4 mg once daily. Lower doses, like 1 or 2 mg saw minor improvement, and higher doses up to 8 mg did not improve results further than 4mg.
1.6 cc BAC in 16mg vial = 1mg per 10 units. Typical dose would then be 40 units daily, and the vial would last 4 days.
BPC-157
The FDA is meeting with the Pharmacy Compounding Advisory Committee (PCAC) on 7/23/26 to evaluate BPC-157 for the treatment of ulcerative colitis.
BPC is for soft tissue injury repair. Half life 6-8 hrs. Local injection at an injury site is best, but systemic (in the stomache area) works quite well too. People often mix this with TB-500 in the same vial, but I recommend against that. Those two peptides have a different PH and a different half life. Also different optimal dosing schedules. Keep them separate. A study on using BPC-157 for regeneration can be found here.
BPC-157 significantly stimulates epigenic change in over 100 types of genes, and does so very quickly. It’s biggest effect is in stimulating angiogenesis, or the building of capillaries and veins, which in turn helps growth and repair factors flow to damaged tissue. The way it does that is through influencing the genes that transcript nitric-oxide use. It improves how your body utilizes nitric oxide that’s existing, and how your body makes more nitric oxide more efficiently.
Here are a couple of Youtube short videos on it. The first is a Joe Rogan interview, and the second is from a well-known Stanford University professor, Dr. Andrew Huberman:
https://www.youtube.com/shorts/EVejn72GgQo
https://www.youtube.com/shorts/kOUvJVD_78U
Dr. Trevor Bachmeyer calls it a “forever peptide”, to be taken daily, and talks extensively about BPC-157 in this video:
Here are some studies on it:
https://pubmed.ncbi.nlm.nih.gov/34267654/
https://pubmed.ncbi.nlm.nih.gov/40756949/
I believe that the claim that some have made regarding BPC-157 enabling cancer growth to be false. In a cancer study, here is an article showing that in vitro, BPC-157 stopped human melanoma cell growth and reduced VEGF signaling. https://journals.lww.com/melanomaresearch/citation/2004/08000/bpc_157_inhibits_cell_growth_and_vegf_signalling.50.aspx. And in mice with colon cancer cachexia, BPC-157 reduced muscle wasting and prolonged survival: https://pubmed.ncbi.nlm.nih.gov/29898649/
Dosage: 300mcg to 600mcg daily.
5mg vial with 2cc BAC = 20 units daily = 500mcg/dose.
10mg vial with 2cc BAC = 10 units daily = 500mcg/dose.
10mg vial with 3cc BAC = 10 units for 333mcg.
If your kangaroo can tolerate daily injections, then inject BPC-157 daily, and TB-500 every 3 to 5 days.
Cagrilintide
Weight loss. Operates on different receptors than semaglutide or tirzepatide, so is often stacked with one of them. It activates central amylin receptors to promote satiety, slow gastric emptying, and reduce food intake. Cagrilintide plus semaglutide is called CagriSema. CagriSema is in clinical trial by Novo.
Dosage: Weekly. If stacked with another GLP-1, dose it at about 1/4 the dosage of the other. For example, 8mg of Tirzepatide (or Retatrutide) would be stacked with 2mg of Cagrilintide.
10mg vial with 2cc BAC = 20 units per mg.
12.5mg vial with 2.5cc BAC = 20 units per mg.
Cartalax
Similar to BPC-157.
Dosage: 2mg per day, 5 days per week. After workout, on empty stomach.
20mg vial with 2cc BAC = 10 units per mg.
Cerebrolysin
Very good at treating Alzheimer’s, vascular dementia, stroke, or traumatic brain injury.
The above are “heavy hitter” doses for severe problems. If you are generally healthy and using it as a recovery tool after a hard work day, 1 to 5 ml works pretty good.
IM Dosage: Up to 5 ml* Cerebrolysin can be administered intramuscularly over 3 minutes. Try it first thing in the morning, either the day of if you are trying to drive performance for that day, or the day after for recovery.
Typically a 10 ml ampule has 2000mg of Cerebrolysin, so 1 to 5 ml is 200mg to 1000mg.
CJC-1295 no DAC (usually paired with Ipamorelin)
GH release. Half life is about 30 minutes. Stimulates grehlin release, which increases hunger. Consider Tesamorelin instead if you don’t want to stimulate grehlin release.
In research models, CJC 1295 (No DAC) has been associated with:
- Increased physiological GH release
- Elevated IGF-1 signaling
- Support for recovery, tissue repair, and body composition studies
- Preservation of normal pituitary responsiveness
Potential observations are generally mild and may include transient water retention or injection site irritation.
If you compare CJC with Tesamorelin, Tesa is more associated with reduction of visceral fat and improved lipolysis, whereas CJC is more for recover and tissue repair. Both are GH releasers.
Dosage: 100-500mcg daily. No more than 2000mcg per week. Evening, or after workout. Recommend 5 days a week, then 2 days off. Do this for a cycle of 12 weeks, then 4 weeks off. You don’t want to overdrive the pituitary gland in generating GH, and doing non-stop stimulation of GH is thought to possibly have that risk.
5/5 blend (CJC/Ipa), with 2.5cc BAC, 15 units daily = 300mcg per dose. 5 days per week.
CJC-1295 with DAC (usually paired with Ipamorelin)
GH release. Half life (with DAC) is 7-8 days. Stimulates grehlin release, which increases hunger. Consider Tesamorelin instead if you don’t want to stimulate grehlin release.
See the section on CJC-1295 no DAC for more information.
Dosage: 1-2mg each dose, taken twice a week.
12.5mg vial with 2cc BAC, 20 units = 1.25mg per dose.
Dihexa
Reports say it is good for cognitive decline and neurodegenerative diseases. Most sources endorse it as an Oral.
Dosage: 5-10mg per day. Most sources are 8mg tables, so one tablet per day.
DSIP
A 9-amino acide peptide named by Swiss researchers in the 1970’s as “Delta Sleep Inducing Peptide”.
The FDA is meeting with the Pharmacy Compounding Advisory Committee (PCAC) on 7/24/26 to evaluate DSIP for for opioid withdrawal, chronic insomnia, and narcolepsy.
DSIP-like material has been found in human brain, plasma, pituitary tissue, and even breast milk, which strongly suggests it’s part of our endogenous physiology. It touches the hypothalamus and pituitary, tweaks stress hormones like ACTH and cortisol, nudges luteinizing hormone and growth hormone, and influences neurotransmitters tied to stress, mood, and pain. Because of all that it does, current researchers seem to refer to it less as a sleep inducer and more as a circadiam rhythm peptide that just happens to help with sleep.
In a chronic pain pilot study, 6 out of 7 patients with things like migraines, psychosomatic pain, and tinnitus-associated pain had significant pain reduction after DSIP therapy. Many of these cases were long-standing and hard to treat. Their depressive symptoms improved alongside the pain.
In small insomnia trials (including a multi-study series by Schneider-Helmert and colleagues), insomniacs given DSIP for a few nights saw complete normalization of sleep patterns. Sleep architecture returned to the range seen in people without insomnia after just four nights of treatment. No next-day hangover and actually better daytime alertness and cognitive performance than placebo.
In cancer research, mice injected monthly with DSIP had a 2.6-fold drop in spontaneous tumors and lived 24% longer. https://pubmed.ncbi.nlm.nih.gov/12782416/
Dosage: 100-500mcg daily, cycled. 10 days on, 5 days off.
For defense against Alzheimer’s, stack it with Epitalon and MOTS-C
5mg vial 2cc BAC, 20 units = 500mcg
Epitalon / Epithalon
Increase telomerase length. May help prevent or delay cognitive decline.
25% Lifespan Increase in Rats
The FDA is meeting with the Pharmacy Compounding Advisory Committee (PCAC) on 7/24/26 to evaluate Epitalon for insomnia.
Professor Vladimir Dilman and Dr. Ward Dean had co-authored a paper where it was noted by Dilman that in rats, the epithalamine biopeptide increased the lifespan by twenty-five per cent. The paper was entitled The Neuroendocrine Theory of Aging and Degenerative Disease. These Epithalon (Epitalon) studies were later confirmed by Russian Academy Sciences in Moscow Professor Vladimir Khavinson.
Cellular Regeneration
This peptide was discovered that causes telomerase production reactivation in the cells, which allows telomerase to become repaired. This results in the body’s rejuvenation down to the cellular level of your genes. The effects of pineal gland secretion are simulated by this simple tetrapeptide, thus activating the telomerase production in cells.
Senile and Elderly Individuals
The research done by Professor Khavinson was done on senile and elderly individuals that indicated mortality was reduced by almost half when this peptide was administered.
Predictive of Mortality
In elderly subjects, there have been established links between the shortening of a telomere and early mortality. This is how telomeres are considered synonymous to a human being’s biological clock. As these shorten progressively through continuous division of cells, they signal the onset of aging and death, ultimately. It the production of telomeres can be stimulated, cells in the body would not have a limit of time and would then continuously renew and replicate, slowing down the aging effects as a result.
EPITHALON (Epitalon) Effect on Life Span
Research studies prove that telomere lengths actually increase after the administration of the Epithalon (Epitalon) peptide on research subjects. After twelve years of Epithalon (Epitalon) peptide administration, the studies done by scientists proved a thirty to fifty per cent life span increase compared to those that did not receive EPITHALON (Epitalon). This translates to about seven extra years of excellent health and living. Clinical studies only lasted for twelve years and this produced seven extra years.
Cancer Research
Lifelong dosing in mice cut leukemia development by 6-fold. https://pubmed.ncbi.nlm.nih.gov/14501183/. And in HER-2/neu mice, Epitalon reduced tumor number, tumor size, and lung metastasis. https://pubmed.ncbi.nlm.nih.gov/12209581/
Dosage: 5-10mg per day, 5 days per week, 2 to 3 weeks per cycle, two or three cycles per year. Any time.
50mg vial with 2cc BAC, 20 units daily = 5mg per dose.
10mg vial with 2cc BAC, 40 units = 2mg
GHK
This is not GHK-Cu– see the discussion following this one for GHK-Cu.
A lot of the clinical benefits of GHK are enhanced with the Cu, so if you eliminate the Cu you might not get the same benefits that you had hoped for compared with GHK-Cu. Using just GHK will likely require more serum copper support.
To use GHK topically:
If your GHK is lyophilized freeze dried powder in a vial, you should first reconstitute it in the same way as you would GHK-Cu. If it came in a 3cc vial, you will only be able to put 3cc of BAC water in. 100mg vial with 3cc BAC will equal 3.33mg per 10 units.
At this point, you can further reconstitute it into a simple carrier — an unscented, fragrance-free lotion or gel base, or even diluted further in bacteriostatic water for a spray/mist application. Apply to clean, dry skin. Common areas of interest: face, scalp, or localized scarring/healing sites.
To use subcutaneously:
Injecting GHK, without the copper “Cu”, doesn’t sting like injecting GHK-Cu does. This is the route most peptide users default to when they want more predictable systemic exposure rather than relying on topical penetration.
GHK was originally isolated from human plasma specifically because of its extraordinarily high binding affinity for Cu²⁺ — it binds copper more tightly than albumin does, which is the main copper-carrying protein in blood. This is actually why Pickart’s early research treated GHK and GHK-Cu somewhat interchangeably; free GHK introduced into a copper-containing environment (like blood) has a strong tendency to scavenge loosely-bound or exchangeable copper and form the complex in situ, rather than staying as bare peptide.
So injecting “plain” GHK subq isn’t necessarily injecting something that stays functionally distinct from GHK-Cu — it may pick up copper from your own serum copper pool (normally a small but real free/exchangeable fraction, distinct from ceruloplasmin-bound copper) shortly after administration. Whether it picks up enough to replicate a deliberately-dosed GHK-Cu complex is genuinely unclear and not something with good human data — but it’s not automatically “inert” in the way, say, an unrelated random peptide with no metal affinity would be.
The in vitro literature that separates “GHK-alone” from “GHK-Cu” effects does show differences — some gene expression and wound-healing assays behave differently depending on whether copper is bound, suggesting the copper really matters mechanistically, not just as a delivery gimmick.
There’s a real chance GHK will behave partially like GHK-Cu once in circulation. But it’s also not a confident substitute; you’re relying on your own serum copper to do the complexing job that manufacturing normally does deliberately and controllably. If you want to hedge toward that outcome rather than leave it to chance, that’s really the only place where oral or dietary copper timing might matter — not combined in the vial, but ensuring you’re not copper-deficient at the time of injection, since a copper-replete state is the mechanism by which it could self-complex at all.
Bottom line:
Take copper supplements when taking GHK (and not GHK-Cu).
The RDA for copper is 900 mcg/day for adults. Most people already get 700–1,500 mcg/day from a normal diet (organ meats, shellfish, nuts, seeds, dark chocolate, whole grains all have meaningful copper). The tolerable upper limit is 10,000 mcg (10 mg)/day. That’s a wide margin — you’re not threading a needle between deficiency and toxicity, you’re just making sure you’re not on the low end.
Practical approach without bloodwork:
- A modest supplement — 1–2 mg/day (1,000–2,000 mcg) — taken for a few days to a week before you plan to use the GHK would reasonably ensure you’re not copper-depleted, without approaching the 10 mg UL by a wide margin.
- You don’t need to supplement continuously — copper stores in the liver, so a short loading period before injection is a more sensible approach than daily long-term dosing, and it limits your cumulative exposure.
- Copper bisglycinate or copper gluconate are generally better tolerated on the GI tract than copper sulfate, if you have a choice.
- Take it separately from zinc or high-dose vitamin C supplements if you take those, since both interfere with copper absorption.
Symptom self-monitoring as your safety net (without doing bloodwork):
Given the wide margin between RDA and UL, at 1–2 mg/day you’re very unlikely to see any toxicity symptoms of too much copper. But as a practical check: watch for nausea, GI upset, or metallic taste in the days you’re supplementing — those would show up well before anything more serious, and they’re your signal to stop, not push through.
One more consideration:
Don’t take the copper supplement and inject the GHK at the exact same time expecting instant complexation — the idea is that day(s)-prior supplementation gives your serum/exchangeable copper pool a chance to be adequately stocked, so it’s available when the GHK is circulating, not that the two need to coincide to the hour.
This seems like a reasonable, low-risk way to give your GHK a real shot at behaving more like GHK-Cu, without the expense of testing or the complexity of trying to pre-form the complex yourself.
GHK-Cu
GHK-Cu (glycyl-l-histidyl-l-lysine copper) is a naturally occurring copper peptide used primarily for anti-aging, skin regeneration, hair growth, and wound healing. It acts as a signaling molecule to boost collagen and elastin production, reduce inflammation, and improve skin elasticity.
Most often, you’ll find GHK-Cu copper peptides (usually listed in ingredient lists under the name Copper Tripeptide-1) in various cosmetics, with skin care products being some of the most popular use cases. According to a 2018 review, GHK-Cu has demonstrated the ability to:3
- Tighten loose skin
- Reverse age-related skin thinning
- Repair the skin’s protective barrier proteins
- Improve skin firmness and elasticity
- Reduce the appearance of fine lines and wrinkles
- Smooth rough skin
- Stimulate wound healing
- Lessen the appearance of photodamage (sun damage), hyperpigmentation, skin spots, lesions, and more
- Reduce inflammation and damage from free radicals
- Increase hair growth and thickness
Additionally, in research from 2015, the authors noted that GHK-Cu may be able to stimulate collagen, regulate the skin remodeling process, attract immune cells to the site of an injury, and restore “replicative vitality to fibroblasts” (a cell that helps form connective tissue) in patients who’ve undergone radiation therapy for cancer.2 6
In cancer research, GHK-Cu reversed 70% of overexpressed genes in metastatic colon cancer and activated 6 of 12 cell-death genes. https://neoplasiaresearch.com/index.php/jao/article/view/217 . And in another research study, it m odulated cancer-related gene expression in breast and prostate cancer cell lines. https://www.lidsen.com/journals/genetics/genetics-05-02-128
Dosage: 1mg to 3mg per day. Any time.
50mg vial with 2.5cc BAC, 10 units daily = 2mg per dose.
80mg vial with 3.5cc BAC, 10 units daily = 2.3mg per dose.
80mg vial with 3cc BAC, 10 units daily = 2.67mg per dose.
100mg vial with 10cc BAC, 10 units daily = 1mg per dose.
100mg vial with 6cc BAC, 10 units daily = 1.67mg per dose.
100mg vial with 5cc BAC, 10 units daily = 2mg per dose.
100mg vial with 3cc BAC, 10 units daily = 3.33mg per dose.
100mg vial with 3.5cc BAC, 10 units daily = 2.85mg per dose.
For topical serum, mix 1 gram of raw GHK-Cu powder with 25cc of Hyaluronic Acid. This will give you a 4% GHK-Cu serum. Apply the serum topically to your skin.
Glutathione
Antioxidant, detoxification, immune support, reduction of inflamation. Fertility support (increases sperm motility).
Glutathione is a tripeptide, but functionally it’s the master antioxidant and the liver’s lead janitor. Every time you burn fat, process alcohol, or deal with environmental toxins, your liver is cranking through oxidative stress. Without enough glutathione, that stress turns into damage.
It helps clear toxins released by shrinking fat cells, supports mitochondrial function, and keeps your liver membranes, DNA, and enzymes protected while the heavy lifting is done.
Research has shown that natural glutathione levels decline with age, which may increase cellular vulnerability to oxidative stress. Because of these broad protective functions, glutathione is considered essential for sustaining healthy mitochondrial activity and overall cellular homeostasis.
Glutathione works just like American Wellness advertises. However…
I prefer injectable Glutathione over an IV push. It is faster and more convenient to administer, and I can custom tailor the dose (I choose lower dosages done more frequently). It is also cheaper, at only a few dollars per 100mg injection.
I split the 600mg dosage that American Wellness does into 100mg doses, taken as needed, but at most twice weekly for two weeks. If I do a two week schedule, it is a micro-dosing schedule done over two weeks instead of a sudden 600mg blast you would get from American Wellness.
To get a 100mg dose, I mix 3cc of bacteriostatic water with a 600mg vial of Glutathione. This yields a 100mg dose @ 50 units (1/2 cc), pulled via an insulin syringe.
Glutathione injection should be intramuscular (into muscle), whereas most peptides are injected subcutaneous (into fat). I prefer my thigh.
I will use glutathione if I am feeling worn out, sore, and tired, and I can’t seem to kick the feeling with more sleep, rest, and/or exercise. I find a glutathione shot to be a better pain reliever and muscle relaxer than Tylenol®, and it wakes me up like a splash of cold water.
Shortly after injection, I get a warm tingly sensation all over my body. Then over the next hour or two, an obvious diminishment of soreness (inflamation), and a wide-awake feeling.
Dosage: 100mg to 200mg per dose, every other day, until max of 600mg to 1200mg. Any time of the day. One month on, one month off. Always IM, not subcutaneous.
600mg vial with 3cc BAC, 50 units per 100mg dose = 6 doses per vial.
1500mg vial with 5cc BAC, 50 units per 150mg dose = 10 doses per vial
HCG (Human Chorionic Gonadotropin)
HCG for Men
Commonly prescribed to help address the symptoms of hypogonadism, low testosterone, and infertility. Testosterone deficiency is typically accompanied by fatigue, stress, a low sex drive, and depression. HCG increases testosterone and sperm, which can help reduce infertility and restore sexual desire/drive. Perhaps unexpectedly, HCG may be able to minimize or prevent such side effects from the consumption of anabolic steroids as gonad shrinkage, dropping sperm count, and infertility.
In men, HCG acts like luteinizing hormone (LH). LH stimulates Leydig cells in the testicles, which results in the production of testosterone. LH stimulates production of sperm within structures in the testicles (the “seminiferous tubules”). As HCG stimulates the testicles to produce testosterone and sperm, the testicles grow in size over time.
Dosage: 250-500ius, 3x/week
5000iu vial mixed with 2cc BAC = 500iu per 20 units
HCG for Women
A glycoprotein that is produced during pregnancy and is produced by the placenta. It plays a vital role in maintaining pregnancy and supporting fetal development. It thickens the uterine lining, and signals the body to cease menstruation and create more estrogen and progesterone.
HCG injections can increase the chances of becoming pregnant when used in combination with either IVF (in vitro fertilization) or IUI (intrauterine insemination). It works by inducing ovulation (the release of an egg by the ovaries). If you have a history of infertility, monitoring HCG levels early on in the pregnancy can determine if a successful pregnancy has occurred.
A shot of HCG is considered a trigger shot, and once given, triggers ovulation within 36 hours.
The HCG hormone may increase the chances of multiple pregnancies, which may be a high risk to both the mother and babies. Discontinue HCG immediately after conception.
Dosage: 250-500ius, 3x/week
5,000iu vial with 2cc BAC = 500iu per 20 units.
Humanin
Similar effects as MOTS-C. Some people get fatigued with MOTS-C, and for those people, Humanin may be a better choice. Also, for neurodegenerative diseases (Alzeihmers, etc.), it might be better than MOTS-C. In models of Alzheimer’s disease, Humanin has shown promise in reducing neuronal cell death and modulating amyloid-beta toxicity.
Current studies of Humanin seem to be focused on aging, neurodegeneration, and metabolic disease. Another promising area is for Macular Degeneration.
Our Humanin comes from Limitless Biotech, and here’s some additional information they provide:
Dosage: 100-200mcg per day. It is thought that the best time to take it is post-workout, or in times of high stress. This timing can help maximize its protective effects during recovery.
5mg vial with 2.5cc BAC = 15 units daily = 150mcg/dose.
Ipamorelin
Ipamorelin is a GH releasing peptide. Stimulates Ghrelin (makes you hungry). Half life 2-3 hours. If you instead want a GH releasing peptide that doesn’t stimulate ghrelin, use Tesamorelin.
Usually paired with CJC-1295. They are both GH releasers, but along different pathways, and very synergistic with each other.
Dosage:
- Anti-aging & wellness:
200–300 mcg per day, typically in one or two doses. - Muscle growth or fat loss:
300–500 mcg per day, with dosing split into AM and PM injections for more stable GH release.
10mg vial with 2cc BAC = 500mcg per 10 units.
Recommend 5 days a week, then 2 days off. Do this for a cycle of 12 weeks, then 4 weeks off. You don’t want to overdrive the pituitary gland in generating GH, and doing non-stop stimulation of GH is thought to possibly have that risk.
Kisspeptin-10
Testosterone support. Recommend pairing it with Testagen. Kisspeptin may serve as a natural alternative to HCG for maintaining fertility and hormonal balance in testosterone therapy. It stimulates LH and testosterone production, helping restore the HPG axis.
Dosage: 100-400mcg once every 48-72 hours. 10-12 wks on, 4-6 wks off. Inject any time.
5mg vial with 2.5cc BAC, 10 units = 200mcg.
KPV
Skin health, psoriasis, eczema. Wound healing (a bit like BPC-157). Reduces inflamation.
The FDA is meeting with the Pharmacy Compounding Advisory Committee (PCAC) on 7/23/26 to evaluate KPV for for wound healing and inflammatory conditions.
Referred by some doctors as “The Greatest Anti Inflammatory Ever”.
Inflamed and damaged tissues are always pumping out “signals” (certain proteins). Those tissues upregulate certain transporters and exhibit increased vascular permeability. In other words, the inflamed tissue is screaming with biochemical distress signals. KPV is drawn to those areas like a magnet, and in doing so, finds and targets the inflamed tissue specifically, regardless of where you initially injected the KPV. Healthy normal tissue doesn’t even see the KPV, while the damaged tissue is flooded with it.
A Journal of Pharmacology in Experimental Therapeutics study used a model with two groups of mice with Colitis. One group was given subq injections of KPV, while the control group got Saline injections. The KPV group had dramatic reductions of the disease, and inspection of the colon tissue showed massive protection, with no inflammatory cells, and almost zero ulceration. Also showed reduced clinical severity of arthritis, and CT scans showed profound reduction in bone erosion.
KPV is noted for its high safety profile and its ability to treat inflammatory skin conditions (eczema, psoriasis, acne). It is considered a promising, naturally occurring anti-inflammatory agent that works in part by reducing microbial burden.
In a 2011 study, Journal for Investigative Dermatology studied KPV in 67 patients with moderate to severe psoriasis. The study was 12 weeks (3 months), and the Psoriasis Area and Severity Index (the PASI score) decreased 62%.
Similar results with Eczema. In 2015, “Alergy” examined 54 patients with moderate to severe eczema, and the EASI score (Eczema Area and Severity Index) decreased 58%.
Dosage: 100-500mcg, one to two times per day. Systemically works well, but locally at the problem site is better.
For skin conditions, suggest starting at 200mcg and titrating up from there, plus stacking it with TB-500 3mg every 3 days.
10mg vial with 2.5cc BAC, 10 units = 400mcg.
12.5mg vial with 2.5cc BAC, 10 units = 500mcg.
Melanotan-2
- Tanning effect: MT-II stimulates melanin production in the skin, leading to tanning-like darkening. This is due to MC1 receptor activation.
- Appetite and weight: Some melanocortin receptor activation (notably MC4R) is linked to reduced appetite and potential weight loss in animal and early human studies.
- Sexual function: MT-II has been reported to increase libido in some user reports and small studies, likely via central MC receptors.
- Erection: There are anecdotal reports of improved erectile function, again tied to MC receptor activity.
- Potential side effects: Nausea, flushing, increased blood pressure, yawning, diffuse darkening of skin, and in some cases tachycardia or anxiety. There are reports of more serious adverse events in some contexts.
Dosage: 150-500mcg.
10mg vial with 3cc BAC = 167mcg per 5 units.
MOTS-C
“Exercise in a bottle“– it’s an exercise mimetic peptide. Anti-aging. Bone health. MOTS-C is an AMPK upregulator, which boosts glucose uptake. In other words, it tells your cells “it’s daytime”. It also delays melatonin release. This means it can keep you awake, and give you energy. Only take this in the morning. Taking it late in the day can lead to insomnia.
The FDA is meeting with the Pharmacy Compounding Advisory Committee (PCAC) on 7/23/26 to evaluate MOTS-C for obesity and osteoporosis.
In experimental models, MOTS-c has demonstrated the ability to enhance exercise endurance, insulin sensitivity, and mitochondrial biogenesis. It effectively signals cells to shift toward energy efficient metabolic states, similar to what occurs during exercise or caloric restriction.
Research in the American Journal of Physiology confirms that it helps with fat loss by forcing fatty acid oxidation– i.e., it causes the body to burn fat instead of glucose.
A 2019 study (Hepatology) showed that it reverses fatty liver disease.
A 2022 study in Neuroscience Review indicates that it upregulates BDNF (Brain Derived Nuerotropic Factor), which appears to stall or even reverse alzheimers.
“MOTS-C doesn’t make you smarter, it just fixes the energy crises that is making you stupid”
JACC Journals found that it improves heart function after a heart attack in less than 12 hours, by making heart muscles’ mitochondria more efficient and reducing cell death, which means you don’t get a bunch of fibrotic tissue.
In a 2024 Cell Reports paper, MOTS-c reversed MASH (metabolic dysfunction-associated steatotic liver disease) in mice, leading to less liver fat, less cell death, less inflammation, and less fibrosis.
Another 2025 Scientific Reports study showed MOTS-c plus exercise actually improved diabetic liver fibrosis by activating the Keap1-Nrf2 antioxidant pathway and suppressing TGF-β/Smad pro-fibrotic signaling.
Better mitochondrial function, less scar tissue.
Another peptide, TB-500, can repair fibrotic tissue, while MOTS-C can help insure it doesn’t get created to begin with. These seem like a very good pairing if you use them together.
MOTS-c is your “make your liver and muscles act like an athlete” shot.
Comparing MOTS-C SS-31:
MOTS c is generally explored in models focused on fat metabolism, glucose regulation, endurance, and metabolic flexibility, due to its effects on AMPK activation and cellular energy adaptation.
SS 31, by contrast, is more commonly studied in models involving mitochondrial dysfunction, fatigue, and oxidative stress, where improving ATP efficiency and mitochondrial stability is the primary objective.
Because they target different aspects of mitochondrial biology, combination research involving both compounds is increasingly common. MOTS c acts primarily as a metabolic signaling peptide, helping cells adapt to energetic stress. SS 31, by contrast, works directly at the level of the mitochondrial membrane, improving the efficiency of ATP production machinery itself.
Dosage: 0.5-1mg 3-5x per week., or 2.5-5mg 1-2x per week. I personally lean towards 3mg every 3 days. Cycle 4 weeks on, 2 weeks off.
You should start at an even lower dose than the above at the beginning (maybe about half), because about 30% of people will get a histamine reaction for the first couple of shots. So start lower, then titrate up to regular dosage.
10mg vial with 1cc BAC = 1mg per 10 units, or 3mg per 30 units.
30mg vial with 1.5cc BAC = 2mg per 10 units, or 5mg per 25 units.
NAD+
Increases cognitive clarity and memory. Enhances physical energy and endurance. Increases insulin sensitivity similar to MOTS-C. Mechanism for all of this is believed to be through increased cell oxygenation.
NAD+ is being studied for Seizure, Alzheimer’s, Diabetes, Obesity, Chronic Inflammation, Osteoarthritis, Sleep Disorders, Depression, Anxiety, Schizophrenia, Epilepsy, ADHD, Chronic Pain, Exercise Performance, Metabolic Syndrome.
When NAD+ levels are low, several adverse effects can occur due to its essential role in cellular processes. One of the primary consequences is a decline in cellular energy production, as NAD+ is crucial for converting nutrients into ATP, the cell’s main energy currency. This energy deficit can lead to increased fatigue, reduced physical performance, and general lethargy. Additionally, low NAD+ levels impair the function of sirtuins, proteins that regulate inflammation, stress resistance, and cellular repair. This impairment can accelerate aging and increase susceptibility to age-related diseases.
Furthermore, insufficient NAD+ hinders DNA repair processes, leading to genomic instability and a higher risk of mutations and cancers. The decline in NAD+ also affects mitochondrial function, potentially resulting in neurodegenerative diseases and cognitive decline due to reduced brain cell protection and maintenance. Metabolic health can be compromised as well, increasing the risk of conditions such as obesity, diabetes, and cardiovascular diseases. Overall, maintaining adequate NAD+ levels is crucial for sustaining energy production, cellular health, and longevity, and its deficiency can have wide-ranging negative impacts on overall health and well-being.
Can stack NAD+ with Glutathione, 5-Amino-1MQ, Epitalon, SS-31. Also stacks well with MOTS-C and Retatrutide.
American Wellness does 500mg to 1500mg IV infusions. Their website also states:
* Reduced withdrawal symptoms such as fatigue, headaches, nausea, and anxiety.
* Improved cognitive clarity and reduced brain fog
* Support for neurotransmitter balance, especially dopamine and serotonin
* Liver and cellular repair after long-term alcohol use
* Fewer cravings and more emotional stability
* Improved sleep and energy levels during early detox
* Faster recovery time from physical and neurological symptoms
Dosage:
Every other day until vial is empty. Administrate subq.
LOW: 20-100mg per shot. MODERATE: 100-250mg per shot .
500mg vial with 1.5cc BAC = 100mg per 30 units, 250mg per 75 units.
750mg vial with 1.5cc BAC = 125mg per 25 units, 250mg per 50 units.
Oxytocin
Social bonding, stress relief, dopamine increase, and improved social behavior.
Dosage: 50-100mcg. Can stack with PT-141. 5 days per week. This is 100 to 200 doses per 10mg vial, so you will need a larger vial for more BAC.
10mg vial with 10cc BAC = 1mg per 100u = 100mcg per 10u.
Pinealon
Cognitive enhancer. Also helps with Alzheimer’s and other neurological issues. Synergistically stacks well with Vesugen. Also stacks well with DSIP and Epithalon, but Vesugen should probably be preferred if you don’t want to take all four (Pinealon, Vesugen, DSIP and Epithalon). Should be cycled.
Pinealon is a natural bioregulatory peptide complex designed to support the brain and central nervous system by optimizing neuronal metabolism, gene expression, and antioxidant defenses.
Studies on Pinealon have demonstrated its ability to modulate the expression of genes involved in apoptosis regulation and neurotrophic support, helping preserve neuronal integrity under conditions of stress, hypoxia, or aging. It reduces programmed cell death in the brain and increases the brain’s ability to neutralize oxidative stress. It has been shown to normalize levels of lipid peroxidation and enhance antioxidant enzyme activity, suggesting a strong neuroprotective effect. These mechanisms contribute to improved focus, memory, and mental resilience in experimental models of cognitive decline and neurodegenerative conditions.
Pinealon appears to influence neuronal gene expression, synaptic function, and protection against oxidative stress. In experimental models, it has been associated with:
- Improved memory and cognitive performance
- Enhanced neuronal plasticity
- Reduced oxidative damage
- Support for brain aging and neuroprotection
Cognitively, we see improvements in memory, learning, and mental clarity. Mood-wise, Pinealon boosts serotonin, modulates cortisol, and improves HPA-axis resilience.
Dosage: 2mg per dose for 10 days (20mg cycle).
20mg vial with 2cc BAC = 2mg per 20 units
PT-141
Enhances bonding.
Dosage: 500-1,000mcg
10mg vial with 2cc BAC = 10 units per 500mcg. No more than twice per week, or desensitization might occur.
Retatrutide
Retatrutide (reta) is referred to as a “triple agonist”. An “agonist” is a receptor that turns on certain signals in the body, like hunger, insulin release, etc. Reta activates 3 of them: (1) GIP, (2) GLP-1, and (3) Glucagon. The GIP signal helps regulate insulin and appetite. GLP-1 slows digestion and reduces hunger. Glucagon helps influence energy burning and fat metabolism. I think of it as a 3rd generation weight loss peptide, with tirzepatide (Monjouro and Zepbound) the 2nd generation (they only activate GIP and GLP-1), and semaglutide (Ozempic) the 1st generation (it only activates GLP-1).
Reta is currently (Nov 2025) in Phase 3 human trials. Phase 2 trial results were published October 2025 in the New England Journal of Medicine. Here is a link to the phase 2, double-blind, randomized, placebo-controlled trial:
https://www.nejm.org/doi/full/10.1056/NEJMoa2301972
Weight Loss: Results are substantially better than with semaglutide (Ozempic) or tirzepatide (Monjauro). At 48 weeks, a weight reduction of 5% or more, 10% or more, and 15% or more had occurred in 92%, 75%, and 60%, respectively, of the participants who received 4 mg of reta; 100%, 91%, and 75% of those who received 8 mg. The most common adverse events in the reta groups were gastrointestinal; these events were dose-related, were mostly mild to moderate in severity, and were partially mitigated with a lower starting dose (2 mg vs. 4 mg). Dose-dependent increases in heart rate peaked at 24 weeks and declined thereafter.
Other Benefits: Treatment with reta was associated with improvements in cardiometabolic measures (exploratory end points) including systolic and diastolic blood pressure and levels of glycated hemoglobin, fasting glucose, insulin, and lipids (with the exception of high-density lipoprotein [HDL] cholesterol).
Reta has been associated with improvements in lipid profiles, including reductions in triglycerides, LDL, and VLDL cholesterol. It also showed a significant reduction in blood pressure in both T2DM and obese patients.
Reta has also shown potential benefits on kidney function, with significant reductions in urine albumin-to-creatinine ratio (UACR) and increases in estimated glomerular filtration rate (eGFR) in obese patients.
Reta’s ability to influence liver triglyceride concentrations forms another critical area of research. In clinical trials, reta has exhibited a capacity to decrease hepatic fat content, confirming its prospect for treating NAFLD and enhancing overall liver function. Such observations underscore the therapeutic implications of reta beyond mere weight loss into essential metabolic health.
Lilly published their TRIUMPH-4 Phase 3 data in December 2025 for retatrutide.
28.7% weight loss. 71 pounds average. At 68 weeks. Here’s what happened:
445 people with obesity and knee osteoarthritis. Split into three groups – 9mg retatrutide, 12mg retatrutide, and placebo. The 12mg group lost an average of 71.2 pounds. That’s 28.7% of their starting weight. And 8 percentage points higher than tirzepatide’s ~21% in Phase 3.
This trial was designed for knee osteoarthritis, not just weight loss. The pain results were massive:
• 76% reduction in pain scores
• 74% improvement in physical function
• 12% of people completely pain-free by week 68
(Study) Journal for ImmunoTherapy of Cancer – 4 November 2025
Subcutaneous tumors were established in diet-induced obese male mice. Animals were randomized into four groups, including a control group of sterile water. The RETA group had a 3-fold reduction in tumor size compared to the control group.
Treatments were administered every three days for two weeks, beginning post-tumor cell injection. Tumor growth was assessed using digital calipers, and splenic immune profiling was performed at endpoint via high-dimensional spectral flow cytometry.
Findings demonstrate that low-dose RETA exerts anti-tumor effects in a preclinical pancreatic cancer model, independent of weight loss. Ongoing studies in additional models aim to determine mechanisms mediating RETA’s potent anti-tumor function. RETA may have direct anti-tumor and/or anti-tumor immunity actions that contribute to improved tumor outcomes.
Other Endorsements: A very interesting endorsement is this one by Dr. Trevor Bachmeyer. He states that in his opinion the weight loss aspects of reta are the least important of the benefits, and he gives compelling reasons for that in this video:
He says that in his opinion semaglutide (Ozempic) and tirzepatide (Monjauro) are trash and should be thrown away, and reta used instead. He talks about “why” in this video:
https://www.youtube.com/watch?v=JJZzjJhP2rQ
Both videos cite many different scientific studies, but the last one probably cites the most.
Dosage: Weekly injection (it has a half life of 8 days)
For obesity, the standard protocol is to start at 2mg per week for one month, and then titrate up from there. I recommend 1.5mg the first week so that you can monitor side-effects, and then 2mg for the next 3 to 5 weeks. Slowly titrate up from there (in 0.5mg increments per week), depending on how you feel. Trials peaked at 12mg per week. Many people don’t see a lot of results until after around 3mg per week.
Dosage is around 0.5mg weekly for people that are not overweight but want other benefits of retatrutide.
16mg vial with 1.6cc BAC = 1mg per 10 units. 16mg vial with 3.2cc BAC = 500mcg per 10 units.
60mg vial with 3cc BAC = 2mg per 10 units. (80mg = 40 units)
Selank
Similar to Semax. Purportedly, Semax is better for cognitive decline, and Selank is better for anxiety and/or depression.
Increases GABA release in the brain. Selank has a very short half-life (~2–3 minutes in plasma), which is why multiple daily administrations are usually used in research.
Dosage: 100mcg – 500mcg per dose, one or two times per day.
10mg vial with 1cc BAC water = 5 units per 500 mcg.
Semaglutide
Weight Loss. Single agonist (GLP-1). Goes under the brand names Ozempic and Wegovy. Not recommended. Has more side effects, and is less effect, than tirzepatide, retatrutide, or cagrilintide.
Recommend stacking this with Cagrilintide, in the same syringe. The result is called “Cagri-sema”.
Dosage: Start with 2mg. Titrate up another 2mg every month. If stacking with Cagrilintide, use 1/4 as much Cagri and you do Sema.
Semax
For neurodegenerative issues (Dementia, Alzheimer’s, Parkinson’s). Has cognitive function and memory formation mechanisms. Also neuroprotection in stroke and injury models.
The FDA is meeting with the Pharmacy Compounding Advisory Committee (PCAC) on 7/24/26 to evaluate Semax for cerebral ischemia, migraine, and trigeminal neuralgia.
Dosage: 200–600 mcg/day, often cycled (10–14 days on, 2–3 off); effects build over 3–7 days
30mg vial with 3cc BAC water = 5 units per 500 mcg.
SS-31
SS-31 is a mitochondria-targeted peptide that binds to cardiolipin in the inner mitochondrial membrane and stabilizes the electron transport chain. That means more ATP, fewer leaks, and less ROS (Reactive Oxygen Species).
In metabolic disease models, SS-31 has been shown to reduce mitochondrial ROS and lipid peroxidation, increase ATP, and preserve mitochondrial structure in liver tissue. In preclinical studies, this has been associated with improvements in muscle endurance, cardiac energy output, and cellular resilience to oxidative stress.
A 2024 review highlighted SS-31 as a key candidate for restoring mitochondrial function and mitigating liver injury by targeting oxidative stress at its source.
In research models, SS 31 has been associated with:
- Improved mitochondrial ATP efficiency
- Reduced reactive oxygen species and oxidative stress
- Enhanced cellular energy output, particularly in muscle, heart, and brain tissue
- Increased resilience in models of mitochondrial dysfunction
Comparing SS-31 to MOTS-C:
MOTS c is generally explored in models focused on fat metabolism, glucose regulation, endurance, and metabolic flexibility, due to its effects on AMPK activation and cellular energy adaptation.
SS 31, by contrast, is more commonly studied in models involving mitochondrial dysfunction, fatigue, and oxidative stress, where improving ATP efficiency and mitochondrial stability is the primary objective.
Because they target different aspects of mitochondrial biology, combination research involving both compounds is increasingly common. MOTS c acts primarily as a metabolic signaling peptide, helping cells adapt to energetic stress. SS 31, by contrast, works directly at the level of the mitochondrial membrane, improving the efficiency of ATP production machinery itself.
Dosage:
Daily for 4 to 6 weeks (for general mitochondrial health). Any time.
LOW: 1-2mg per injection. MODERATE: 2-5mg per injection. HIGH: 5-10mg per injection.
25mg vial with 2.5cc BAC = 1mg per 10 units = 5mg per 50 units.
40mg vial with 3.6cc BAC = 1mg per 9 units = 5mg per 45 units.
60mg vial with 3cc BAC = 2mg per 10 units
TB-500
Soft tissue injury repair. Systemic injection. There’s evidence that it can repair fibrotic heart muscle tissue after a heart attack.
TB-500 might help for kidney repair. It is highly angiogenic, and the kidney’s are very vascular in nature.
The FDA is meeting with the Pharmacy Compounding Advisory Committee (PCAC) on 7/23/26 to evaluate TB-500 for wound healing.
In 2010 there was a study in Circulation that TB-500, following an MI (myocardial infarction, or heart attack) in mice resulted in reversal of the fibrotic tissue damage of the MI.
2012, Journal of Pharmacology and Therapeutics showed TB-500 promotes wound healing.
Annals of the New York Academy of Sciences shows TB-500 inhibits migration and invasion of gleoblastoma cells (gloeblastoma is a highly aggressive brain cancer). In doing so, it interferes with the same actin dynamics that cancer cells use to mestastasize.
TB-500 might also help with ED, by reversing penile fibrotic tissue damage. The penile fibrotic tissue damage can be because of diabetes, high blood pressure, infections, or other various vascular problems.
It also helps with the repair of damaged nerves, by promoting the growth and projections of neurites.
The angiogenic properties of TB-500 can help with diabetic ulcers.
Some people will combine this with BPC-157, in the same syringe. I recommend against that. BPC and TB have different PH’s, and different half lifes. They also have different “optimal” dosing schedules. So, inject them separately. However, the two are definitely synergistic in their effect, which means you should put them both in your stack. Some people refer to this as the “Wolverine Stack”, because of how well they heal together.
Dosage: I have concluded that TB-500 is best dosed in larger “pulses”, not smaller daily microdoses. Smaller doses might not be adequate for proper cell signaling. An analogy is like trying to hear a whisper in a noisy room. If you want to be heard, you need to turn the volume up.
I think I prefer 10mg vial with 1cc BAC, then take 50 units (which would be 5mg) every 5 days. This amount results in using 1/2 of a 10mg vial with each injection. Do this for (maybe) four of the 10mg vials (40 days), then rest for about 4 weeks.
Tesamorelin
Tesamorelin is FDA-approved for medical use. Clinical dosing protocols are well known and offer a well-defined foundation. Does not stimulate Ghrelin, so is preferable to CJC-1295 and Ipamorelin for overweight people.
If you compare Tesamorelin with CJC-1295 (both of which are GH releasers), CJC-1295 is more for tissue repair and recovery, whereas Tesamorelin is more for body fat reduction.
1. Visceral Fat Reduction
Tesamorelin is clinically proven to reduce visceral adipose tissue (VAT)—the dangerous fat stored around internal organs, which is linked to insulin resistance, inflammation, and cardiovascular risk.
For physique athletes, this means a tighter midsection, improved vascularity, and a leaner abdominal profile—without compromising muscle mass.
2. Increased IGF-1 and Growth Hormone Activity
Tesamorelin increases endogenous GH and IGF-1, which drive:
* Muscle growth
* Fat metabolism
* Cellular repair
* Skin and connective tissue rejuvenation
3. Muscle Preservation During Fat Loss
Tesamorelin helps maintain lean muscle tissue even in a calorie deficit. This is key for bodybuilders, performance athletes, or anyone entering a cutting phase who wants to preserve size while leaning out.
4. Enhanced Recovery and Sleep Quality
Many users report deeper sleep, better recovery, and reduced inflammation, likely due to Tesamorelin’s role in supporting growth hormone rhythms and systemic repair.
* Improved sleep = better training response
* Faster muscle repair = more frequent training
* Reduced joint pain = longer training longevity
5. Potential Anti-Aging and Cognitive Benefits
Emerging research suggests Tesamorelin may improve mitochondrial function and cognitive performance due to its impact on IGF-1 and neurotrophic factors, although more studies are needed.
Dosage: 1-2mg daily, before bed. Fasted 2-3 hrs before shot. You might consider combining this with CJC-1295 (no DAC) and Ipamorelin.
Typical cycling is 8-12 weeks, then rest for a few weeks. You don’t want to overdrive the pituitary gland in generating GH, and doing non-stop stimulation of GH is thought to possibly have that risk.
5mg vial with 2.5cc BAC 50 units daily = 1mg per dose.
5mg vial with 1cc BAC 20 units daily = 1mg per dose.
24mg vial with 2.4cc BAC 10 units daily = 1mg per dose.
Testagen
Testagen is capable of normalizing testosterone production as well as thyroid hormone production in certain settings. Some report enhanced libido. Recommend pairing with Kisspeptin-10.
Dosage: 2mg daily
20mg vial with 2cc BAC = 20 units for 2mg
Thymosin Alpha-1 (or TA-1)
Immune support, and anti-depressant. 1-6mg per week. Use when you feel a sickness coming on.
Here is a study on it: https://pmc.ncbi.nlm.nih.gov/articles/PMC11762651/
Many people who struggle with depression do not present as “sick.” They present as tired, inflamed, unmotivated, flat, anxious, or disconnected. Underneath that presentation, however, there is often chronic low-grade immune activation or immune dysregulation that TA-1 addresses.
TA-1 is the most clinically documented immune peptide we have. Many other countries were smart enough to approve it long ago. We’re just behind here. It has been approved in around 37 countries under the name Zadaxin, and over 600,000 patients have used it in clinical settings. We’re talking about large trials, meta-analyses, a phase-three sepsis program, and a deep base of cancer literature.
The easiest way to picture it is a thermostat for your immune system. When your immune response is weak or worn out, it brings it up. When it’s overheated and starting to attack your own body, it brings it back down. It just nudges you toward wherever balance is for you in that moment. So it’s more of a modulator than a booster.
You also make less TA-1 during serious illness. Chronic infections, sepsis, cancer, and big physical stress all drive your own production down. So your body pulls back on it right when you need it the most. That’s kind of the whole point of supplementing. When you need it most is exactly when you make the least.
Use Cases
The most obvious one is the older adult with a fading immune system. Think late 60s and up, the person who catches everything and takes forever to get over it.
Then theres people with lingering fatigue. A lot of these folks have exhaused T cells. The cells are still there, they’ve just stopped working, and TA-1 helps wake them back up.
It also has real data in cancer studies, though that’s always something to run with your oncologist. And worldwide, chronic hep B is actually its strongest indication of all.
Also high output, high stress, high travel situations. When you are jet lagged and constantly getting thrown into new environments.
Who doesn’t need it? Healthy adults who already feel good. If your immune system is already running well, there’s nothing there for it to modulate.
Dosage: 0.5-2.0mg, 2-3 times per week.
3mg vial with 1cc BAC and 25 units per dose = 0.75mg per dose.
10mg vial with 1cc BAC = 20 units for 2mg
Tirzepatide
Weight Loss. Dual agonist (GIP/GLP-1). Superior to Semaglutide. Brand names are: Mounjaro and Zepbound.
Dosage: 2.5mg to 15mg per week. 5 day half life. Start low, go slow.
60mg vial with 3cc BAC = 10 units for 2mg, 12.5 units for 2.5mg, 25 units for 5mg, or 50 units for 10mg.
Vesugen
Research has shown it to protect the vascular system from the effects of aging by limiting the development of atherosclerosis and decreasing overall endothelial cell dysfunction. Is activated as a result of calorie restriction and is therefore thought to be one of the proteins responsible for the profound anti-aging effects associated with calorie restriction. May help break addictions. Might help with Alzeimers. Reportedly activates, stimulates, and supports stem cells for accelerated healing.
Good to combine with Pinealon.
Dosage: 500mcg, injected daily.
20mg vial with 3cc BAC = 15